Movement Disorders (revue)

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Striatal and Cortical β-Amyloidopathy and Cognition in Parkinson's Disease.

Identifieur interne : 000062 ( Main/Exploration ); précédent : 000061; suivant : 000063

Striatal and Cortical β-Amyloidopathy and Cognition in Parkinson's Disease.

Auteurs : Neha Shah [États-Unis] ; Kirk A. Frey [États-Unis] ; Martijn L T M Müller [États-Unis] ; Myria Petrou [États-Unis] ; Vikas Kotagal [États-Unis] ; Robert A. Koeppe [États-Unis] ; Peter J H. Scott [États-Unis] ; Roger L. Albin [États-Unis] ; Nicolaas I. Bohnen [États-Unis]

Source :

RBID : pubmed:26380951

Abstract

Although most previous cognitive studies of β-amyloidopathy in PD focused on cortical plaque deposition, recent postmortem studies point to an important role of striatal β-amyloid plaque deposition. The aim of this study was to investigate the relative contributions of striatal and cortical β-amyloidopathy to cognitive impairment in PD.

DOI: 10.1002/mds.26369
PubMed: 26380951


Affiliations:


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<div type="abstract" xml:lang="en">Although most previous cognitive studies of β-amyloidopathy in PD focused on cortical plaque deposition, recent postmortem studies point to an important role of striatal β-amyloid plaque deposition. The aim of this study was to investigate the relative contributions of striatal and cortical β-amyloidopathy to cognitive impairment in PD.</div>
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